Fresh frozen plasma administration do no mix kcentra with other medicinal products. How to insert a pdf into powerpoint online tech tips. An industrysponsored, prospective, randomized, openlabel, active controlled, multicenter phase iiib, noninferiority study comparing kcentra n 88 and ffp n 88 has completed in november 2012. Prothrombin complex concentrates in trauma and perioperative.
The pdf file should be the first option within the insert dialog window. Emergent reversal of anticoagulation in the ed and icu settings. Please see full prescribing information for kcentra, including boxed warning, on page 42. Kcentra must be used within 4 hours following reconstitution. Kcentra is not approved for reversal of dabigatranrelated bleeding. Beriplex the package insert uses the trade names beriplex and kcentra interchangeably. Powerpoint does not insert pdfs as images so the following is the easiest method that allows you to.
Prospective evaluation of a fixeddose 4factor prothrombin. Find patient medical information for kcentra intravenous on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Kcentra administration reminders kcentra preparation and. Acrobat can detect the orientation of the majority of the text in your presentation and rotate the resulting pdfs so that the text is horizontal. Regional clinical practice guidelines for the rapid. Click convert button on the bottom toolbar and wait for converting process finish. Heparin reversal protamine sulfate adjust for time elapsed since last dose. Novoseven rt coagulation factor viia, recombinant for hcp. Click the image and it will be inserted into the slide. Use a separate, unused mix2vial transfer set for each product vial kcentra is manufactured by csl behring gmbh and distributed by csl behring llc. Because beriplex is marketed under the name kcentra in the united.
An industrysponsored, prospective, randomized, openlabel, active controlled, multicenter phase iiib, non. Emerging anticoagulation reversal issues in emergency medicine gabby anderson, pharmd. In healthy individuals, administration of a single iv infusion. Fixed versus variable dosing of 4factor prothrombin. The fdaapproved dosing is 25 to 50 iu factor ix per kilogram of body weight, depending on. This document is provided in portable document format pdf. Recently, our hospital instituted a protocol where all doses of 4fpcc were a fixed dose of 1500 iu. Pcc may partially correct ptaptt but will not affect antifactor xa activity and will not increase drug clearance. Turn the package over and insert the plastic spike through diluent stopper.
If you received a lengthy deck that is a pdf, you basically received pictures of each slide. Antithrombotic therapy and prevention of thrombosis, 9thed. The mechanism of action of pccs is important for understanding their therapeutic applications. Andexxa coagulation factor xa recombinant, inactivatedzhzo is a recombinant modified human factor xa fxa protein indicated for patients treated with rivaroxaban or apixaban, when reversal of. Kcentra is also contraindicated in patients with disseminated intravascular coagulation. Finally, find your converted pdf files and try to insert pdf into powerpoint. Although prior fda labeling submission requirements have been in the ms word and pdf formats, the fda now requires the package insert portion of. Microsoft powerpoint tutorial to setup files for print. Mean in vivo recovery of factors ii, vii, ix, x, and proteins c and s following a single iv infusion of kcentra in patients with acute major. Kcentra prothrombin complex is a blood coagulation factor replacement product.
Annexa4 interim data set, prior to day 30 from the prescribing information. Kcentra is a purified, heattreated, nanofiltered and lyophilized nonactivated fourfactor prothrombin complex concentrate human prepared from human u. American college of chest physicians evidencebased clinical practice guidelines. Kcentra is for use in adults and dosing is based on body weight. In normal view, on the slide with the pdf file, click the pdf files icon or image, and then on the insert tab, in the links group, click action. Units of factors are ratiobased as compared to factor ix, e. Finally, find your converted pdf files and try to insert pdf into powerpoint on mac. Mean in vivo recovery of factors ii, vii, ix, x, and proteins c and s following a single iv infusion of kcentra in patients with acute major bleeding was 2, 2. Kcentra is used to quickly reverse the effects of a bloodthinning medicine such as warfarin during a major. Kcentra is a blood coagulation factor replacement product indicated for the urgent reversal of. Urgent warfarin reversal kcentra has over 20 years of clinical experience as beriplex outside the us. Launch powerpoint 2016, and make sure that the guides are visible. Grip the package at its edge and pull the package off the device.
In the following window, make sure standard and not minimum size is chosen. Search for and locate the pdf file you want to insert. Inserting a pdf as an image is a quick way to present flat data in a noninteractive fashion. Kcentra is used to quickly reverse the effects of a bloodthinning medicine such as warfarin during a major bleeding episode, or when there is a need for emergency surgery or invasive medical procedure. The most common indication for treatment was intracranial hemorrhage 28, 71.
Kcentra preparation and reconstitution instructions kcentra. From insert menu, choose object and then from file once i selected that pdf and any other pdf later i got the following alert message. Home kcentra prothrombin complex concentrate human. You cant insert or edit pdf content when youre editing a presentation in powerpoint online or for the web. Dec 08, 2015 you typically add more guides in powerpoint using the dragtospawn process that we explain on this page. Kcentra will be stored at room temperature in the pharmacy department at all times. In this case, youll insert the entire pdf into the presentation as an object on a powerpoint slide, which you can open and view during presentation by selecting the pdf object on the slide. In the action settings box, select the mouse click tab if you want to open the pdf with a click, or the mouse over tab if you want it to open when you move the pointer over the pdf file icon. May 21, 2009 how to import pdf s into powerpoint 1. Kcentra quick guide app kcentra prothrombin complex. Regional clinical practice guidelines for the rapid treatment. Youll find that only two guides, one horizontal and.
Singledose kcentra 4fpcc the only fdaapproved alternative to plasma for urgent warfarin reversal. Practically it is easy to get the image into powerpoint and display it but it always loses quality and is never of a standard that i would use to present to large. Superior inr reduction at 30 minutes after end of infusion vs plasma. If cooled, the solution should be warmed to 2025c prior to administration.
Four factor pcc kcentra is dosed on the amount of factor ix. Send text medication prices vary by pharmacy location or chain and are subject to change. Open the emf file in powerpoint and ungroup twice to edit it. Powerpoint does not insert pdfs as images so the following is the easiest method that allows you to place pdf imagespages onto your slides note. Additionally you can also use the guide options in powerpoint 2016 to add new guides. Open the package of baxject device by peeling away the lid without touching the inside. Take this kcentra coupon to your nearest rite aid pharmacy to receive your discounted price. The proposed package insert document is usually created in microsoft word and submitted as part of the final labeling folder. Do not send powerpoint files to a commercial printer, they will not print. Then adjust the powerpoint application window size so you can drag the file in.
The quality of the pdf file is reduced with this method, but you can open the full pdf file by doubleclicking the image when viewing or editing in normal view. How to insert an image from pdf into powerpoint without. It contains the vitamin k dependent coagulation factors ii, vii, ix and x, and the antithrombotic proteins c and s. How to insert an image from pdf into powerpoint without losing resolution i have been trying to take an image from part of a pdf document and insert it into powerpoint 2011 for mac. How much factor is in a vial of pcc versus a unit of ffp. Emergent reversal of anticoagulation in the ed and icu. Fourfactor prothrombin complex concentrates 4fpccs are emerging as the standard of care for emergent warfarin reversal due to their ability to rapidly and effectively achieve hemostasis. Working with powerpoint in office 365 business on a macbook pro running with macos sierra 10. Left click on it and drag the pdf file onto the slide to insert it into powerpoint.
Please see accompanying full prescribing information, including. Regional clinical practice guidelines for the rapid treatment of age 65 head injury patients age 65 head injury patient with any of the following. Insert pdf content into your presentation either as a picture that shows on your slide, or as a document that you can open during your slide show. One vial of pcc also contains factors ii, vii, ix, x, proteins c and s, antithrombin iii and a small amount of heparin. Andexxa coagulation factor xa recombinant, inactivatedzhzo is a recombinant modified human factor xa fxa protein indicated for patients treated with rivaroxaban or apixaban, when reversal of anticoagulation is needed due to lifethreatening or uncontrolled bleeding. It is ideal for presenting data contained within other. May 3, 2018 summary basis for regulatory action andexxa. One vial of pcc also contains factors ii, vii, ix, x, proteins c and s, antithrombin iii and a small amount.
Once you have made guides visible on your powerpoint slides, they show up in the same position on all other slides within the presentation. Novoseven rt coagulation factor viia, recombinant is a drug focused on effective bleed control treatment for your patients with hemophilia a or b with inhibitors, congenital factor vii deficiency, glanzmanns thrombasthenia with refractoriness to platelets, and acquired hemophilia. This indication is approved under accelerated approval based on the. Is there a scientific rationale for the use of pcc as a reversal agent for xa. Download the complete prescribing information for kcentra.
Kcentra beriplex in europe fii 380800 u fvii 200500 u fix 400620 u fx 5001020 u protein c 420820 u protein s 240680 u small amount of heparin, human albumin, antithrombin iii kcentra prothrombin complex concentrate prescribing information. Microsoft powerpoint emerging anticoagulation reversal issues in emergency medicine g. Reversal of oral factor xa inhibitors by prothrombin complex. How to import pdfs into powerpoint linkedin slideshare. Emerging anticoagulation reversal issues in emergency. Hit start conversion and then click download once its ready. Andexxa coagulation factor xa recombinant, inactivated. The package insert is also submitted in pdf and spl format. Dosing of kcentra based upon specific anticoagulantrelated bleeding note. Insert pdf file content into a powerpoint presentation. Kcentra, prothrombin complex concentrate human, is a blood coagulation factor replacement product indicated for the urgent reversal of acquired.
Insert pdf file content into a powerpoint presentation powerpoint. Kcentra preparation and reconstitution instructions. Powerpoint embeds the pdf and displays an adobe acrobat icon. Recheck inr 30 minutes after kcentra dose kcentra4factor pcc dose based on actual body weight up to 100kg. Instructional guide an instructional guide reconstitution of kcentra ial ransfer set please see full important safety information inside. Multiple vials of reconstituted kcentra may be pooled in. Discard partially used vials multiple vials are usually required. Evaluation of fixed dose 4factor prothrombin complex. Download the inkscape application its free and is available for various platforms go here and convert your. Cannot redose kcentra direct oral anticoagulants doac rivaroxaban xarelto, apixaban eliquis, or edoxaban savaysa last dose taken within 35 halflives of doac yes or unknown kcentra 50 unitskg iv x 1 max dose.
Please see accompanying full prescribing information, including boxed warning. The optimal dose of 4fpcc is currently unknown despite multiple studies evaluating different dosing regimens. Prescribing information kcentra prothrombin complex. In the insert object dialog box, click create from file. Turn the package over and insert the plastic spike through diluent. In the insert object box, select create from file, and then enter the pdf file location. Kcentra is contraindicated in patients with known anaphylactic or severe systemic reactions to kcentra or any of its components including heparin, factors ii, vii, ix, x, proteins c and s, antithrombin iii and human albumin. Kcentra is for single use only and must be used within 4 hours following reconstitution. Package insert reference guide for pharmacy students. I was asked to insert a pdf in the ppt presentation file and so i followed these steps. Apr 22, 2020 kcentra prothrombin complex is a blood coagulation factor replacement product.